Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668924 | 0.98 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL15185827 | 0.92 | SMN1; SMN2 (0.55) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL5693542 | 0.92 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL24508669 | 0.90 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL19983194 | 0.90 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL12566095 | 0.90 | SMN1; SMN2 (0.56) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL8342578 | 0.88 | HPGD (0.53) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL18947953 | 0.88 | HPGD (0.53) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL21771222 | 0.88 | MEN1 (0.48) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 | |
| SCHEMBL21771287 | 0.88 | MEN1 (0.48) | KDM4EMAPK1HIF1APAOXSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015668-A1 | CONJUGATED PROTEINS WITH PROLONGED IN VIVO EFFICACY | NOVO NORDISK A/S (DK) | 2010-02-11 | — | — | WO | disclosed |