Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983194 | 1.00 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL23946005 | 0.92 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL5668924 | 0.92 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL23560302 | 0.91 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXACHE | |
| SCHEMBL22525950 | 0.91 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXACHE | |
| SCHEMBL13494530 | 0.90 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL24848355 | 0.90 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL22340557 | 0.86 | KDM4E (0.64) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL25517112 | 0.86 | KDM4E (0.64) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL22340559 | 0.85 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |