Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834947 | 0.92 | ADH5 (0.55) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL1835007 | 0.89 | ADH5 (0.56) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL16480968 | 0.89 | ADH5 (0.56) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL1847134 | 0.89 | ADH5 (0.56) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL1834965 | 0.89 | ADH5 (0.53) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL1839530 | 0.89 | ADH5 (0.53) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL1826262 | 0.89 | ADH5 (0.55) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL1826552 | 0.89 | ADH5 (0.55) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL12556796 | 0.89 | ADH5 (0.55) | ADH5CYP2C19MAPTPOLBTP53 | |
| SCHEMBL13494871 | 0.88 | ADH5 (0.69) | ADH5CYP2C19MAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019903-A1 | NOVEL PYRROLE INHIBITORS OF S-NITROSOGLUTATHIONE REDUCTASE AS THERAPEUTIC AGENTS | N30 PHARMACEUTICALS, LLC (US) | 2010-02-18 | — | — | WO | disclosed |