Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310647 | 0.90 | POLB (0.35) | POLB | |
| SCHEMBL7005606 | 0.80 | POLB (0.31) | POLB | |
| SCHEMBL13185397 | 0.72 | POLB (0.37) | POLB | |
| SCHEMBL10037571 | 0.72 | POLB (0.37) | POLB | |
| SCHEMBL2610530 | 0.71 | POLB (0.36) | POLB | |
| SCHEMBL12107536 | 0.70 | CYP1A2 (0.43) | POLB | |
| SCHEMBL13448309 | 0.69 | POLB (0.35) | POLB | |
| SCHEMBL327611 | 0.68 | SMN1; SMN2 (0.35) | POLB | |
| SCHEMBL10037551 | 0.67 | POLB (0.38) | POLB | |
| SCHEMBL13448321 | 0.67 | GSK3A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021720-A1 | CONJUGATES OF SMALL-INTERFERING NUCLEIC ACIDS | NEKTAR THERAPEUTICS (US) | 2010-02-25 | — | — | WO | disclosed |