SCHEMBL7005606

SCHEMBL7005606

C=C1C=CC(=O)N1C(C)C(=O)NC(C)NC(=O)CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13448309 0.80 POLB (0.35) POLB
SCHEMBL13494969 0.80 POLB (0.32) POLB
SCHEMBL12505905 0.79 HTT (0.35) POLB
SCHEMBL11955679 0.75 POLB (0.32) POLB
SCHEMBL11955673 0.74 POLB (0.32) POLB
SCHEMBL12421897 0.74 POLB (0.32) POLB
SCHEMBL2610530 0.73 POLB (0.36) POLB
SCHEMBL10310591 0.72 ALDH1A1 (0.35) POLB
SCHEMBL12507623 0.72 ACACB (0.36) POLB
SCHEMBL10037571 0.71 POLB (0.37) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012065086-A1 CONJUGATES OF AN IL-2 MOIETY AND A POLYMER NEKTAR THERAPEUTICS (US) 2012-05-18 — — WO disclosed
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