Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | GRM5 | P41594 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401834 | 0.88 | ALDH1A1 (0.64) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7406578 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16330805 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL31420284 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4ENPC1RAB9AGRM5 | |
| SCHEMBL25433738 | 0.80 | MAPT (0.50) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL14133117 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL22445661 | 0.79 | KMT2A (0.56) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL6369452 | 0.79 | MEN1 (0.68) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL28610606 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL23400150 | 0.78 | CA1 (0.52) | SMN1; SMN2MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |