Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906238 | 0.87 | KMT2A (0.45) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL9906248 | 0.86 | KMT2A (0.44) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL9906233 | 0.84 | HSD17B10 (0.42) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL9906234 | 0.82 | KMT2A (0.46) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL15034474 | 0.80 | BCHE (0.41) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL9906237 | 0.77 | HSD17B10 (0.38) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL15034449 | 0.75 | BCHE (0.37) | KMT2AHSD17B10CYP2C9MEN1NR1I2 | |
| SCHEMBL30015824 | 0.73 | POLB (0.42) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL13143681 | 0.73 | KMT2A (0.54) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL13143684 | 0.73 | KMT2A (0.54) | KMT2ATARDBPHSD17B10CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017323-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | WO | disclosed |