Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.51 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052790 | 0.91 | MAPK1 (0.65) | MAPK1HTTALDH1A1PIK3CDPIK3CA | |
| SCHEMBL22507416 | 0.91 | MAPK1 (0.74) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL13495703 | 0.88 | MAPK1 (0.54) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL13495650 | 0.87 | HTT (0.50) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL13495748 | 0.85 | PIK3CA (0.54) | MAPK1HTTALDH1A1PIK3CDPIK3CA | |
| SCHEMBL22507417 | 0.83 | MAPK1 (0.68) | MAPK1HTTTSHRALDH1A1KDM4E | |
| SCHEMBL22507480 | 0.83 | HTT (0.67) | MAPK1HTTGRIA1CACNG8CACNG2 | |
| SCHEMBL13495698 | 0.82 | PIK3CA (0.53) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL13495701 | 0.81 | APP (0.50) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1GLA | |
| SCHEMBL13495695 | 0.81 | NPC1 (0.58) | MAPK1HTTALDH1A1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |