Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.53 |
| ▸ | MTOR | P42345 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495703 | 0.82 | MAPK1 (0.54) | PIK3CAPIK3CDMTORMAPK1HTT | |
| SCHEMBL13495653 | 0.82 | MAPK1 (0.66) | PIK3CAPIK3CDMTORMAPK1HTT | |
| SCHEMBL3052790 | 0.79 | MAPK1 (0.65) | PIK3CAPIK3CDMTORNPC1MAPK1 | |
| SCHEMBL13495701 | 0.78 | APP (0.50) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13495700 | 0.76 | PIK3CA (0.50) | PIK3CAPIK3CDMTOR | |
| SCHEMBL13495649 | 0.76 | CYP11B2 (0.64) | PIK3CAPIK3CDMTOR | |
| SCHEMBL13495650 | 0.76 | HTT (0.50) | PIK3CAPIK3CDMTORMAPK1HTT | |
| SCHEMBL13495695 | 0.76 | NPC1 (0.58) | PIK3CAPIK3CDMTORNPC1MAPK1 | |
| SCHEMBL1976848 | 0.75 | NPC1 (0.68) | NPC1MAPK1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13495748 | 0.74 | PIK3CA (0.54) | PIK3CAPIK3CDMTORNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |