Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 17/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242234 | 0.85 | BDKRB1 (0.42) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL2237788 | 0.84 | BDKRB1 (0.44) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL1935724 | 0.83 | BDKRB1 (0.45) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL2235289 | 0.82 | BDKRB1 (0.42) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL12347367 | 0.82 | MCHR1 (0.46) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL2236179 | 0.82 | BDKRB1 (0.52) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL2239167 | 0.81 | KMT2A (0.45) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL2242698 | 0.81 | BDKRB1 (0.62) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL2242580 | 0.81 | BDKRB1 (0.42) | BDKRB1KCNH2MCHR1 | |
| SCHEMBL12347414 | 0.80 | BDKRB1 (0.59) | BDKRB1KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020556-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |