Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268138 | 0.92 | CNR1 (0.51) | CNR1ALDH1A1FAAHEPHX2CNR2 | |
| SCHEMBL16268853 | 0.92 | CNR1 (0.51) | CNR1ALDH1A1FAAHEPHX2CNR2 | |
| SCHEMBL18120322 | 0.90 | CNR1 (0.69) | CNR1ALDH1A1FAAHEPHX2CNR2 | |
| SCHEMBL17467159 | 0.88 | CNR1 (0.72) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14864049 | 0.85 | CNR1 (0.78) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL29989035 | 0.83 | CNR1 (0.81) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL3351989 | 0.79 | CASP2 (0.56) | CNR1ALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL9968526 | 0.79 | CNR1 (0.50) | CNR1ALDH1A1FAAHEPHX2MAPT | |
| SCHEMBL3486494 | 0.79 | EPHX2 (0.69) | CNR1ALDH1A1EPHX2MEN1BLM | |
| SCHEMBL3486112 | 0.79 | EPHX2 (0.69) | CNR1ALDH1A1EPHX2MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019963-A2 | NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |