Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | PRCP | P42785 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349670 | 1.00 | S1PR3 (0.44) | S1PR3CTSSCTSKGPR88MAP2K1 | |
| SCHEMBL1349672 | 1.00 | S1PR3 (0.44) | S1PR3CTSSCTSKGPR88MAP2K1 | |
| SCHEMBL3806048 | 0.94 | S1PR3 (0.36) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL3806041 | 0.94 | S1PR3 (0.36) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL3806038 | 0.94 | S1PR3 (0.36) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL1349938 | 0.77 | MAP2K1 (0.40) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL1349941 | 0.77 | MAP2K1 (0.40) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL1349944 | 0.77 | MAP2K1 (0.40) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL1350902 | 0.76 | MAP2K1 (0.35) | S1PR3GPR88MAP2K1CA12CA1 | |
| SCHEMBL1350905 | 0.76 | MAP2K1 (0.35) | S1PR3GPR88MAP2K1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063085-B2 | Substituted hydantoins | HOFFMANN-LA ROCHE INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20090170920-A1 | SUBSTITUTED HYDANTOINS | CHEN SHAOQING | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170920-A1 | SUBSTITUTED HYDANTOINS | HNMT, HRH3, BRAF | S1PR3 3702/4885CTSS 1187/4885CTSK 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.