Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.75 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.75 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.75 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.75 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987009 | 0.97 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL26709365 | 0.97 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL26702432 | 0.97 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12043072 | 0.97 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15281582 | 0.97 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12965054 | 0.97 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL26345911 | 0.95 | PRSS1 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12256021 | 0.95 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22036033 | 0.95 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16478840 | 0.94 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | DISCOVERX CORPORATION | 2010-02-25 | — | — | US | disclosed |
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | DISCOVERX CORPORATION | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | ERBB2, ALK, ACP1 | F2 3373/4885PRSS1 3811/4885PRSS2 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.