Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.76 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.76 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.76 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.76 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15281582 | 1.00 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12965054 | 1.00 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL26702432 | 1.00 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15987009 | 1.00 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12043072 | 1.00 | F2 (0.76) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL26345911 | 0.98 | PRSS1 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22036033 | 0.98 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12256021 | 0.98 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL13497938 | 0.97 | F2 (0.75) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL17750087 | 0.95 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348516-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348516-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | CHI3L1, CHI3L2, CHIA | F2 3988/4885PRSS1 201/4885PRSS2 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.