Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | THRB | P10828 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | RECQL | P46063 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | BLM | P54132 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | APP | P05067 | 2/20 | 0.74 |
| ▸ | SNCA | P37840 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506103 | 0.96 | MEN1 (0.76) | MEN1KMT2ATHRBHPGDRECQL | |
| SCHEMBL12534472 | 0.90 | CYP1A2 (0.62) | MEN1KMT2ATHRBHPGDRECQL | |
| SCHEMBL13428188 | 0.86 | CYP1A2 (0.64) | MEN1KMT2ATHRBHPGDRECQL | |
| SCHEMBL13330337 | 0.86 | MEN1 (0.79) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL16572423 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL14533441 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL30337894 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL29518427 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL31658969 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL5859460 | 0.85 | MEN1 (0.98) | MEN1KMT2ATHRBHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041068-A1 | DEEPLY QUENCHED ENZYME SENSORS AND BINDING SENSORS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2010-02-18 | — | — | US | disclosed |