Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | THRB | P10828 | 5/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.76 |
| ▸ | RECQL | P46063 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | BLM | P54132 | 3/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | APP | P05067 | 2/20 | 0.76 |
| ▸ | SNCA | P37840 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498718 | 0.96 | MEN1 (0.74) | MEN1KMT2ATHRBHPGDRECQL | |
| SCHEMBL13428188 | 0.90 | CYP1A2 (0.64) | MEN1KMT2ATHRBHPGDRECQL | |
| SCHEMBL13330337 | 0.89 | MEN1 (0.79) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL16572423 | 0.87 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL30337894 | 0.87 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL14533441 | 0.87 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL31658969 | 0.87 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL29518427 | 0.87 | MEN1 (1.00) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL5859460 | 0.86 | MEN1 (0.98) | MEN1KMT2ATHRBHPGDRECQL | |
| Evans Blue Free Acid SCHEMBL29609615 | 0.86 | MEN1 (0.98) | MEN1KMT2ATHRBHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099863-A1 | Compounds for the treatment of demyelinating and autoimmune diseases | UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO (ES) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099863-A1 | Compounds for the treatment of demyelinating and autoimmune diseases | P2RX2, P2RX3, P2RX1 | MEN1 1877/4885KMT2A 3058/4885THRB 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.