Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.74 |
| ▸ | PTP4A3 | O75365 | 3/20 | 0.59 |
| ▸ | CRHBP | P24387 | 2/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.59 |
| ▸ | NAT1 | P18440 | 6/20 | 0.58 |
| ▸ | MYC | P01106 | 2/20 | 0.58 |
| ▸ | MAX | P61244 | 2/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251192 | 0.86 | PIM1 (0.78) | PIM1PTP4A3CRHBPCRHR2NAT1 | |
| SCHEMBL9251195 | 0.86 | PIM1 (0.78) | PIM1PTP4A3CRHBPCRHR2NAT1 | |
| SCHEMBL13499578 | 0.86 | PIM1 (0.62) | PIM1PTP4A3NAT1MYCMAX | |
| SCHEMBL12892060 | 0.85 | PIM1 (1.00) | PIM1PTP4A3CRHBPCRHR2NAT1 | |
| SCHEMBL18102951 | 0.83 | NAT1 (0.74) | PIM1PTP4A3NAT1MYCMAX | |
| SCHEMBL32672283 | 0.83 | NAT1 (0.74) | PIM1NAT1MYCMAXPDE4B | |
| SCHEMBL18102944 | 0.83 | PIM1 (0.74) | PIM1PTP4A3CRHBPCRHR2NAT1 | |
| SCHEMBL18103052 | 0.83 | PIM1 (0.74) | PIM1PTP4A3CRHBPCRHR2NAT1 | |
| SCHEMBL13499581 | 0.81 | MYC (0.78) | PIM1PTP4A3NAT1MYCMAX | |
| SCHEMBL14661291 | 0.81 | PIM1 (0.70) | PIM1PTP4A3CRHBPCRHR2NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |