Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.78 |
| ▸ | CRHBP | P24387 | 2/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.62 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.62 |
| ▸ | NAT1 | P18440 | 7/20 | 0.61 |
| ▸ | MYC | P01106 | 2/20 | 0.57 |
| ▸ | MAX | P61244 | 2/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251192 | 1.00 | PIM1 (0.78) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL12892060 | 0.88 | PIM1 (1.00) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL13499561 | 0.86 | PIM1 (0.74) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL18103052 | 0.86 | PIM1 (0.74) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL18102944 | 0.86 | PIM1 (0.74) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL1247443 | 0.85 | PIM1 (0.62) | PIM1NAT1IGF1R | |
| SCHEMBL1247444 | 0.85 | PIM1 (0.62) | PIM1NAT1IGF1R | |
| SCHEMBL14661291 | 0.83 | PIM1 (0.70) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL13499565 | 0.83 | PIM1 (0.70) | PIM1CRHBPCRHR2PTP4A3NAT1 | |
| SCHEMBL14661290 | 0.83 | PIM1 (0.70) | PIM1CRHBPCRHR2PTP4A3NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5208250-A | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |