Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 4/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAX | P61244 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309671 | 0.87 | NAT1 (1.00) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL8309670 | 0.87 | NAT1 (1.00) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL8310322 | 0.86 | PDE4B (1.00) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL8310325 | 0.86 | PDE4B (1.00) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL8193222 | 0.85 | NAT1 (0.76) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL15347653 | 0.85 | NAT1 (0.76) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL8193225 | 0.85 | NAT1 (0.76) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL29975856 | 0.84 | NAT1 (0.63) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL26931541 | 0.84 | PDE4B (0.70) | NAT1PDE4BCA2GSK3BCISD1 | |
| SCHEMBL26931547 | 0.84 | PDE4B (0.70) | NAT1PDE4BCA2GSK3BCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |