Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191512 | 1.00 | NAT1 (0.63) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL25692662 | 1.00 | NAT1 (0.63) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL26931547 | 0.88 | PDE4B (0.70) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL26931541 | 0.88 | PDE4B (0.70) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL13499562 | 0.84 | NAT1 (0.76) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL8191849 | 0.81 | NAT1 (0.67) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL8191853 | 0.81 | NAT1 (0.67) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL12892054 | 0.79 | NAT1 (0.72) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL8309671 | 0.78 | NAT1 (1.00) | NAT1CA2PDE4BPDE3ACISD1 | |
| SCHEMBL8309670 | 0.78 | NAT1 (1.00) | NAT1CA2PDE4BPDE3ACISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032782-A1 | VACCINE ADJUVANTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO.LTD. (CN) | 2024-02-15 | — | — | WO | disclosed |
| EP-4313962-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2022206725-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-06 | — | — | WO | disclosed |