Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 7/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 3/20 | 0.55 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249066 | 0.83 | TTR (0.69) | MEN1KMT2ANPC1PIM1CISD1 | |
| SCHEMBL1249071 | 0.83 | TTR (0.69) | MEN1KMT2ANPC1PIM1CISD1 | |
| SCHEMBL9573277 | 0.83 | NAT1 (1.00) | NAT1CA2EPHX1ALDH1A1GAA | |
| SCHEMBL9573270 | 0.83 | NAT1 (1.00) | NAT1CA2EPHX1ALDH1A1GAA | |
| SCHEMBL11315685 | 0.81 | NAT1 (0.70) | NAT1CA2EPHX1ALDH1A1MEN1 | |
| SCHEMBL11315688 | 0.81 | NAT1 (0.70) | NAT1CA2EPHX1ALDH1A1MEN1 | |
| SCHEMBL32672283 | 0.81 | NAT1 (0.74) | NAT1CA2EPHX1ALDH1A1GAA | |
| SCHEMBL14661291 | 0.81 | PIM1 (0.70) | NAT1CA2EPHX1PIM1PTP4A3 | |
| SCHEMBL13499576 | 0.81 | PTP4A3 (0.72) | NAT1CA2EPHX1PIM1PTP4A3 | |
| SCHEMBL18102954 | 0.81 | NAT1 (0.70) | NAT1CA2EPHX1PIM1PTP4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206169-B2 | Method for producing benzo[b]thiophene compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20140187782-A1 | METHOD FOR PRODUCING BENZO[B]THIOPHENE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-07-03 | — | — | US | disclosed |
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187782-A1 | METHOD FOR PRODUCING BENZO[B]THIOPHENE COMPOUND | H1-4, H1-0, RB1 | NAT1 806/4885CA2 2200/4885EPHX1 1985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.