SCHEMBL9573270

SCHEMBL9573270

Cc1ccccc1/C=C1\SC(=S)NC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAT1 P18440 5/20 1.00
TTR P02766 1/20 0.72
PIM1 P11309 5/20 0.68
MYC P01106 1/20 0.63
MAX P61244 1/20 0.63
CA2 P00918 1/20 0.62
EPHX1 P07099 1/20 0.62
GSK3B P49841 1/20 0.62
PDE4B Q07343 1/20 0.59
MEN1 O00255 2/20 0.59
ALDH1A1 P00352 2/20 0.59
POLB P06746 2/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
NPC1 O15118 1/20 0.59
MAPK1 P28482 1/20 0.59
RAB9A P51151 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
PSMD14 O00487 1/20 0.58
ALPL P05186 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9573277 1.00 NAT1 (1.00) NAT1TTRPIM1MYCMAX
SCHEMBL32672283 0.85 NAT1 (0.74) NAT1TTRPIM1MYCMAX
SCHEMBL13724876 0.84 TTR (1.00) NAT1TTRPIM1GSK3BMEN1
SCHEMBL7464188 0.84 TTR (1.00) NAT1TTRPIM1GSK3BMEN1
SCHEMBL15091770 0.84 TTR (1.00) NAT1TTRPIM1GSK3BMEN1
SCHEMBL13499564 0.83 NAT1 (0.70) NAT1PIM1CA2EPHX1PDE4B
SCHEMBL8177171 0.82 NAT1 (0.70) NAT1TTRPIM1MYCMAX
SCHEMBL15304598 0.82 NAT1 (0.70) NAT1PIM1MYCMAXCA2
SCHEMBL14226382 0.82 NAT1 (0.69) NAT1PIM1CA2GSK3BMEN1
SCHEMBL18103046 0.82 GSK3B (0.73) NAT1TTRPIM1MYCMAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5306224-A None JP disclosed
EP-2541329-A1 CHARGE CONTROLLING AGENT AND TONER USING SAME Hodogaya Chemical Co., Ltd. (JP) 2013-01-02 EP disclosed
US-20120315576-A1 CHARGE CONTROLLING AGENT AND TONER USING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2012-12-13 US disclosed
US-20120315576-A1 CHARGE CONTROLLING AGENT AND TONER USING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2012-12-13 US disclosed
US-7872027-B2 Low molecular weight Myc-max inhibitors UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2011-01-18 US disclosed
JP-H05306224-A DOPAMINE BETA-HYDROXYLASE INHIBITOR WAKAMOTO PHARMACEUT CO LTD 1993-11-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120315576-A1 CHARGE CONTROLLING AGENT AND TONER USING SAME NPY1R, HCRTR1, CCKAR NAT1 1604/4885TTR 4779/4885PIM1 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.