Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.63 |
| ▸ | PTP4A3 | O75365 | 4/20 | 0.60 |
| ▸ | MYC | P01106 | 1/20 | 0.59 |
| ▸ | MAX | P61244 | 1/20 | 0.59 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 4/20 | 0.52 |
| ▸ | NAT1 | P18440 | 3/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544087 | 0.86 | PIM1 (0.67) | CISD1PIM1PIM2 | |
| SCHEMBL2544089 | 0.86 | PIM1 (0.67) | CISD1PIM1PIM2 | |
| SCHEMBL13499577 | 0.83 | NAT1 (0.64) | PTP4A3MYCMAXCRHBPCRHR2 | |
| SCHEMBL18102941 | 0.81 | NAT1 (0.61) | PTP4A3MYCMAXCRHBPCRHR2 | |
| SCHEMBL13499558 | 0.81 | PTP4A3 (0.71) | CISD1PTP4A3MYCMAXCRHBP | |
| SCHEMBL13499560 | 0.80 | PTP4A3 (0.65) | CISD1PTP4A3MYCMAXCRHBP | |
| SCHEMBL4085089 | 0.79 | PIM1 (0.77) | CISD1MYCMAXADAMTS5CRHBP | |
| SCHEMBL15091393 | 0.79 | PIM1 (0.77) | CISD1MYCMAXADAMTS5CRHBP | |
| SCHEMBL4085086 | 0.79 | PIM1 (0.77) | CISD1MYCMAXADAMTS5CRHBP | |
| SCHEMBL4806036 | 0.78 | CA2 (0.71) | CISD1PTP4A3ADAMTS5CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |