Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.76 |
| ▸ | MAOB | P27338 | 2/20 | 0.76 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.63 |
| ▸ | PIM1 | P11309 | 2/20 | 0.63 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.63 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | CDC7 | O00311 | 1/20 | 0.63 |
| ▸ | PLK4 | O00444 | 1/20 | 0.63 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.63 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | PRKCG | P05129 | 1/20 | 0.63 |
| ▸ | CDK1 | P06493 | 1/20 | 0.63 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.63 |
| ▸ | AKT1 | P31749 | 1/20 | 0.63 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.63 |
| ▸ | CLK2 | P49760 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30841466 | 0.86 | CISD1 (1.00) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL13499560 | 0.80 | PTP4A3 (0.65) | CISD1PIM1NAT1CA2PTP4A3 | |
| SCHEMBL8172590 | 0.78 | CISD1 (0.80) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL8172592 | 0.78 | CISD1 (0.80) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL1641525 | 0.78 | DYRK1A (0.81) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL2199251 | 0.78 | DYRK1A (1.00) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL18102869 | 0.78 | CISD1 (0.71) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL4806036 | 0.78 | CA2 (0.71) | CISD1MAOBDYRK1AGSK3BNAT1 | |
| SCHEMBL2199252 | 0.78 | DYRK1A (1.00) | CISD1MAOBDYRK1APIM1PIM3 | |
| SCHEMBL4801244 | 0.78 | CA2 (0.71) | CISD1MAOBDYRK1AGSK3BNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |