Coenzyme_A

Coenzyme_A

SCHEMBL13500623

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCS

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 3/20 1.00
AURKA O14965 2/20 1.00
CHAT P28329 2/20 1.00
NAA50 Q9GZZ1 2/20 1.00
KAT5 Q92993 2/20 1.00
KAT2B Q92831 1/20 1.00
CREBBP Q92793 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coenzyme_A SCHEMBL29350970 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL29402901 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL26752 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18675521 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18682057 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18033983 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18682056 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18180012 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL26753 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18811987 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100047880-A1 PRODUCTION OF N-ACYLATED SULPHUR-CONTAINING AMINO ACIDS WITH MICROORGANISMS HAVING ENHANCED N-ACYLTRANSFERASE ENZYMATIC ACTIVITY METABOLIC EXPLORER (FR) 2010-02-25 US disclosed