Coenzyme_A

Coenzyme_A

SCHEMBL26753

CC(C)(COP(=O)(O)OP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCS

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 3/20 1.00
AURKA O14965 2/20 1.00
CHAT P28329 2/20 1.00
NAA50 Q9GZZ1 2/20 1.00
KAT5 Q92993 2/20 1.00
KAT2B Q92831 1/20 1.00
CREBBP Q92793 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coenzyme_A SCHEMBL29350970 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL29402901 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL26752 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18675521 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL13500623 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18682057 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18033983 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18682056 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18180012 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18811987 1.00 EP300 (1.00) EP300AURKACHATNAA50KAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 53288 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637656-B2 Recombinant yeast capable of producing caffeic acid and/or ferulic acid ABOLIS BIOTECHNOLOGIES (FR) 2026-05-26 US claimed
EP-4743568-A1 INCREASED PRODUCTION OF ACETYL-COENZYME A AND DERIVED PRODUCTS IN YEASTS DANSTAR FERMENT AG (CH) 2026-05-20 EP claimed
CN-122060817-A Preparation method of citrate-CoA 云南农业大学 2026-05-19 CN claimed
EP-4739291-A2 ADMINISTRATION OF KERATOLYTICS TO OCULAR AND PERIOCULAR SURFACES AZURA OPHTHALMICS LTD (IL) 2026-05-13 EP claimed
EP-4739293-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE DISORDERS AZURA OPHTHALMICS LTD (IL) 2026-05-13 EP claimed
US-12625139-B2 Methods for modulation of acetyltransferase activity and applications thereof including treatments THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2026-05-12 US claimed
CN-122010967-A Organic fluorescent probe compound and preparation method and application thereof 内蒙古大学 2026-05-12 CN claimed
US-20260125717-A1 Bioreactor and Process for Forming Polyhydroxybutyrate Directly from Depolymerized Polyhydroxybutyrate KIMBERLY CLARK CO (US) 2026-05-07 US claimed
US-20260125713-A1 PRODUCTION OF MOLECULES BY PERIPLASMIC ENZYMATIC CATALYSIS BIOC3 (FR) 2026-05-07 US claimed
WO-2026087508-A1 HYDROGELS CONTAINING COVALENTLY LINKED COFACTORS AND METHODS FOR PREPARING THE SAME HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2026-04-30 WO claimed
US-4301244-A TREATING WITH ACYL-COENZYME A SYNTHETASE; OXIDIZING WITH ACYL-COENZYME A OXIDASE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1981-11-17 US claimed
WO-1981001419-A1 METHOD FOR IN ACTIVATING AND MONITORING ANTIBIOTICS AND ASSAYING FOR AMINOGLYCOSIDES WISCONSIN ALUMNI RES FOUND (US) 1981-05-28 WO claimed
US-4246340-A Method and reagent for bioluminiscence LKB-PRODUCTER AB (SE) 1981-01-20 US claimed
US-4169944-A CHOLESTEROL BIOSYNTHESIS INHIBITORS UNIVERSITY PATENTS, INC. (US) 1979-10-02 US claimed
US-4071413-A Method for determining free fatty acids in blood serum using fatty acid activating enzymes ONO PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US claimed
US-4061828-A Modified, grafted mineral carriers RHONE-POULENC INDUSTRIES (FR) 1977-12-06 US claimed
US-4035239-A REACTION WITH ADENOSINE TRIPHOSPHATE, PHOSPHOTRANSACETYLASE ENZYME MCCLOSKEY LEO P 1977-07-12 US claimed
US-3974037-A REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-10 US claimed
US-3935072-A Purification of coenzyme A TANABE SEIYAKU CO., LTD. (JA) 1976-01-27 US claimed
US-3934369-A Vitro net bioxynthesis of chlorophyll and grana UNIVERSITY OF ILLINOIS FOUNDATION (US) 1976-01-27 US claimed