Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 13/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500821 | 0.96 | CYBB (0.73) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500822 | 0.96 | CYBB (0.73) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500863 | 0.89 | CYBB (0.84) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500856 | 0.87 | CYBB (0.70) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500755 | 0.86 | CYBB (0.73) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501262 | 0.86 | CYBB (0.80) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501312 | 0.86 | CYBB (1.00) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500847 | 0.86 | CYBB (0.79) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500845 | 0.86 | CYBB (0.79) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501346 | 0.85 | CYBB (0.83) | CYBBSLC2A1PIM1PIM2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |