Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.67 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 16/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500876 | 0.95 | CYBB (0.68) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500887 | 0.91 | CYBB (0.65) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500888 | 0.91 | CYBB (0.64) | CYBBSLC2A1CHEK1PIM1PIM2 | |
| SCHEMBL13500824 | 0.91 | CYBB (0.66) | CYBBSLC2A1CHEK1PIM1PIM2 | |
| SCHEMBL13500871 | 0.89 | CYBB (0.67) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500953 | 0.89 | CYBB (0.67) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500930 | 0.88 | CYBB (0.73) | CYBBSLC2A1CHEK1PIM1PIM2 | |
| SCHEMBL13500928 | 0.88 | CYBB (0.63) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500878 | 0.84 | CYBB (0.75) | CYBBSLC2A1CHEK1PIM1PIM2 | |
| SCHEMBL13500959 | 0.84 | CYBB (0.80) | CYBBSLC2A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |