Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.73 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 12/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500871 | 0.92 | CYBB (0.67) | CYBBSLC2A1CHEK1MEN1MAPK1 | |
| SCHEMBL13500959 | 0.89 | CYBB (0.80) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500876 | 0.89 | CYBB (0.68) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13501331 | 0.89 | SLC2A1 (0.72) | CYBBSLC2A1PIM1PIM2ALDH1A1 | |
| SCHEMBL13500953 | 0.88 | CYBB (0.67) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500987 | 0.88 | CYBB (0.79) | CYBBSLC2A1CHEK1 | |
| SCHEMBL13500875 | 0.88 | CYBB (0.79) | CYBBSLC2A1CHEK1PIM1PIM2 | |
| SCHEMBL13500872 | 0.88 | CYBB (0.60) | CYBBSLC2A1CHEK1ALDH1A1GAA | |
| SCHEMBL13501329 | 0.88 | SLC2A1 (0.62) | CYBBSLC2A1PIM1PIM2ALDH1A1 | |
| SCHEMBL13500889 | 0.88 | CYBB (0.67) | CYBBSLC2A1CHEK1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |