Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.79 |
| ▸ | CYBB | P04839 | 2/20 | 0.59 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501278 | 0.89 | SLC2A1 (0.82) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501157 | 0.88 | SLC2A1 (1.00) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501301 | 0.87 | SLC2A1 (0.82) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501323 | 0.87 | SLC2A1 (0.82) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501328 | 0.87 | SLC2A1 (0.74) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501294 | 0.87 | SLC2A1 (0.82) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501360 | 0.87 | SLC2A1 (0.79) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501331 | 0.86 | SLC2A1 (0.72) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501291 | 0.85 | SLC2A1 (0.79) | SLC2A1CYBBMAPKAPK2PIM1PIM2 | |
| SCHEMBL13501112 | 0.85 | SLC2A1 (0.79) | SLC2A1CYBBMAPKAPK2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |