Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.72 |
| ▸ | CYBB | P04839 | 2/20 | 0.57 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501329 | 0.93 | SLC2A1 (0.62) | SLC2A1CYBBPIM1PIM2MAPT | |
| SCHEMBL13501293 | 0.92 | SLC2A1 (0.66) | SLC2A1CYBBPIM1PIM2MAPT | |
| SCHEMBL13500930 | 0.89 | CYBB (0.73) | SLC2A1CYBBPIM1PIM2KMT2A | |
| SCHEMBL13501112 | 0.88 | SLC2A1 (0.79) | SLC2A1CYBBPIM1PIM2MAPT | |
| SCHEMBL13501162 | 0.87 | SLC2A1 (0.59) | SLC2A1CYBBPIM1PIM2KMT2A | |
| SCHEMBL13501034 | 0.87 | SLC2A1 (0.59) | SLC2A1CYBBPIM1PIM2MAPT | |
| SCHEMBL13501294 | 0.86 | SLC2A1 (0.82) | SLC2A1CYBBPIM1PIM2MAPT | |
| SCHEMBL13501328 | 0.86 | SLC2A1 (0.74) | SLC2A1CYBBPIM1PIM2MAPKAPK2 | |
| SCHEMBL13501435 | 0.86 | SLC2A1 (0.79) | SLC2A1CYBBPIM1PIM2MAPKAPK2 | |
| SCHEMBL13501362 | 0.85 | SLC2A1 (0.75) | SLC2A1CYBBPIM1PIM2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |