Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL1350592

O=S(=O)([O-])C(F)(F)F.[Li+].[O-][Cl+3]([O-])([O-])O

nearest known ligand 0.35

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL1996959 0.88 GPR3 (0.38) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL29893713 0.84 CA1 (0.44) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL17213 0.84
Trifluoromethanesulfonic Acid SCHEMBL4815937 0.84 CA1 (0.44) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL1318399 0.84 CA1 (0.44) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL31409457 0.81 GPR3 (0.38) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL9276782 0.81 GPR3 (0.38) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL4930505 0.81 CA1 (0.41) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL8214511 0.81 CA1 (0.41) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL1435303 0.81 CA1 (0.41) GPR3CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8064804-B2 Conductive member, process cartridge using the conductive member, and image forming device using the process cartridge RICOH COMPANY, LTD. (JP) 2011-11-22 US disclosed
US-20090142099-A1 CONDUCTIVE MEMBER, PROCESS CARTRIDGE USING THE CONDUCTIVE MEMBER, AND IMAGE FORMING DEVICE USING THE PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-06-04 US disclosed
EP-2065761-A1 Conductive member, process cartridge using the conductive member, and image forming device using the process cartridge Ricoh Company, Ltd. (JP) 2009-06-03 EP disclosed