SCHEMBL13506237

SCHEMBL13506237

Cc1cc(OC[C@H](O)CO)c(F)c(C)c1-c1cccc(COc2ccc(-c3cc(O)ns3)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.40
FFAR4 Q5NUL3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13506239 1.00 FFAR1 (0.40) FFAR1FFAR4
SCHEMBL15061332 0.86 FFAR1 (0.39) FFAR1FFAR4
SCHEMBL9964387 0.83 FFAR1 (0.38) FFAR1
SCHEMBL9935669 0.78 FFAR1 (0.56) FFAR1FFAR4
SCHEMBL13506121 0.77 CD274 (0.43) FFAR1
SCHEMBL13506120 0.77 CD274 (0.43) FFAR1
SCHEMBL13506585 0.73 FFAR1 (0.41) FFAR1
SCHEMBL15552323 0.73 FFAR1 (0.50) FFAR1
SCHEMBL1688187 0.71 FFAR1 (0.47) FFAR1
SCHEMBL16466052 0.70 FFAR1 (0.68) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518060-A1 NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE Mochida Pharmaceutical Co., Ltd. (JP) 2012-10-31 EP disclosed