Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13506237 | 0.86 | FFAR1 (0.40) | FFAR1FFAR4 | |
| SCHEMBL13506239 | 0.86 | FFAR1 (0.40) | FFAR1FFAR4 | |
| SCHEMBL9964387 | 0.81 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL1688187 | 0.69 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL9964353 | 0.66 | FFAR1 (0.46) | FFAR1PPARD | |
| SCHEMBL13506120 | 0.65 | CD274 (0.43) | FFAR1 | |
| SCHEMBL13506121 | 0.65 | CD274 (0.43) | FFAR1 | |
| SCHEMBL9964355 | 0.64 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL28008485 | 0.63 | CYP1A2 (0.48) | — | |
| SCHEMBL2023639 | 0.63 | FFAR1 (0.57) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476287-B2 | 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | claimed |