SCHEMBL1350646

SCHEMBL1350646

NC1=C(O)C=CCC1=Cc1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MIF P14174 4/20 0.41
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
CA2 P00918 8/20 0.36
CA12 O43570 7/20 0.36
KDM4E B2RXH2 1/20 0.36
NAT1 P18440 2/20 0.36
CA1 P00915 2/20 0.35
NFKB1 P19838 1/20 0.35
CA4 P22748 1/20 0.35
CA9 Q16790 6/20 0.34
TRPA1 O75762 1/20 0.33
BCHE P06276 1/20 0.33
GUSB P08236 1/20 0.33
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10616053 0.75 MIF (0.42) MIFTRIM24TRIM33CA2CA12
SCHEMBL7159761 0.69 MIF (0.42) MIFTRIM24TRIM33CA2CA12
SCHEMBL28445292 0.69 MIF (0.44) MIFTRIM24TRIM33NAT1TRPA1
SCHEMBL11385006 0.66 MIF (0.45) MIFTRIM24TRIM33CA2CA12
SCHEMBL14760982 0.65 MIF (0.41) MIFTRIM24TRIM33CA2CA12
SCHEMBL13476075 0.63 TRIM24 (0.50) MIFTRIM24TRIM33CA2CA12
SCHEMBL17691388 0.62 MIF (0.64) MIFKDM4ENFKB1
SCHEMBL3581740 0.62 MIF (0.64) MIFKDM4ENFKB1
SCHEMBL3581744 0.62 MIF (0.64) MIFKDM4ENFKB1
SCHEMBL17691411 0.62 IKBKB (0.64) MIFTRIM24TRIM33NAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6806491-B2 Organic light-emitting devices TSINGHUA UNIVERSITY (CN) 2004-10-19 US claimed
US-20030197465-A1 Organic light-emitting devices TSINGHUA UNIVERSITY (CN) 2003-10-23 US claimed
US-4260437-A CONDENSATION OF SALICYLALDEHYDE WITH AN AMINE UNITED TECHNOLOGIES CORPORATION (US) 1981-04-07 US claimed
US-6410766-B1 None US disclosed
US-12624303-B2 Gasoline additive composition for improved engine performance AFTON CHEMICAL CORPORATION (US) 2026-05-12 US disclosed
EP-4237847-B1 METHODS OF IDENTIFYING A HYDROCARBON FUEL AFTON CHEMICAL CORP (US) 2026-04-01 EP disclosed
US-12553003-B1 Quaternary ammonium compounds AFTON CHEMICAL CORPORATION 2026-02-17 US disclosed
EP-4663720-A1 PARTICULATE REDUCTION IN GDI ENGINES USING MANNICH DETERGENTS Afton Chemical Corporation (US) 2025-12-17 EP disclosed
US-20250376632-A1 PARTICULATE REDUCTION IN GDI ENGINES USING MANNICH DETERGENTS AFTON CHEMICAL CORP (US) 2025-12-11 US disclosed
EP-4345151-B1 GASOLINE ADDITIVE COMPOSITION FOR IMPROVED ENGINE PERFORMANCE AFTON CHEMICAL CORP (US) 2025-11-05 EP disclosed
US-12454653-B2 Gasoline additive composition for improved engine performance AFTON CHEMICAL CORPORATION (US) 2025-10-28 US disclosed
US-5034614-A Treating with carbon dioxide DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1991-07-23 US disclosed
EP-0075174-B1 PROCESS FOR THE PREPARATION OF 4-NITRODIPHENYL AMINES BAYER AG (DE) 1985-08-07 EP disclosed
EP-0147240-A2 Fuel compositions and additive concentrates, and their use in inhibiting engine coking ETHYL CORPORATION (US) 1985-07-03 EP disclosed
US-4482357-A C,P/ CYLIDENE-1,2-PROPANEDIAMINE ETHYL CORPORATION (US) 1984-11-13 US disclosed
US-4482356-A ORGANIC NITRATE ETHYL CORPORATION (US) 1984-11-13 US disclosed
US-4482355-A ORGANIC NITRATE, HYDROCARBYLAMINE, N,N*-DISALICYLIDENE-1,2-PROPANEDIAMINE ETHYL CORPORATION (US) 1984-11-13 US disclosed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US disclosed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP disclosed
US-4260437-A CONDENSATION OF SALICYLALDEHYDE WITH AN AMINE UNITED TECHNOLOGIES CORPORATION (US) 1981-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12553003-B1 Quaternary ammonium compounds PKD2, PKD1, KAT2A MIF 4789/4885TRIM24 3562/4885TRIM33 2033/4885
US-12624303-B2 Gasoline additive composition for improved engine performance SEM1, SUMO2, TAF1 MIF 839/4885TRIM24 3609/4885TRIM33 3930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.