SCHEMBL14760982

SCHEMBL14760982

O=[C]C1=CC=CCC1=Cc1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 4/20 0.41
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
NAT1 P18440 2/20 0.36
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
CA2 P00918 4/20 0.33
CA12 O43570 3/20 0.33
KDM4E B2RXH2 2/20 0.33
NFKB1 P19838 2/20 0.33
CA9 Q16790 2/20 0.33
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
JUN P05412 1/20 0.33
NFE2L2 Q16236 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11570965 0.79 TNF (0.49) NFKB1NPSR1MEN1ALDH1A1KMT2A
SCHEMBL7159761 0.78 MIF (0.42) MIFTRIM24TRIM33NAT1MAPT
SCHEMBL10616053 0.78 MIF (0.42) MIFTRIM24TRIM33NAT1MAPT
SCHEMBL14760931 0.75 MIF (0.40) MIFTRIM24TRIM33NAT1MAPT
SCHEMBL11350548 0.70 MIF (0.36) MIFTRIM24TRIM33NAT1MAPT
SCHEMBL11347030 0.70 MIF (0.36) MIFTRIM24TRIM33NAT1MAPT
SCHEMBL6959499 0.69
SCHEMBL8391117 0.68
SCHEMBL6961530 0.66 KDM4E (0.31) KDM4EMEN1KMT2A
SCHEMBL6956541 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504641-B2 Therapy to reduce extravasation damage PTLNV, LLC, SERIES 6 2016-11-29 US disclosed
US-20130064865-A1 THERAPY TO REDUCE EXTRAVASATION DAMAGE PTLNV, LLC, SERIES 6 2013-03-14 US disclosed