SCHEMBL13508152

SCHEMBL13508152

Cn1c2cc(-c3ccc4c(c3)C(C)(C)c3ccccc3-4)ccc2c2c3ccccc3c3c4ccc(-c5ccc6c(c5)C(C)(C)c5ccccc5-6)cc4n(C)c3c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.38
MAOB P27338 2/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
PDK2 Q15119 7/20 0.36
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAOA P21397 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565470 0.95 MAOB (0.36) LIMK1MAOBRXRARXRBPDK2
SCHEMBL13507780 0.94 LIMK1 (0.34) LIMK1MAOBRXRARXRBPDK2
SCHEMBL13506803 0.88 RXRA (0.37) LIMK1MAOBRXRARXRBPDK2
SCHEMBL13507974 0.87 LIMK1 (0.34) LIMK1MAOBRXRARXRBPDK2
SCHEMBL14478583 0.86 RXRA (0.44) LIMK1MAOBRXRARXRBPDK2
SCHEMBL18565372 0.85 RXRA (0.50) RXRARXRBPDK2NPC1RAB9A
SCHEMBL13507034 0.85 RXRA (0.35) RXRARXRBPDK2NPC1RAB9A
SCHEMBL18565473 0.85 PDK2 (0.33) RXRARXRBPDK2GAAKDM4E
SCHEMBL18565465 0.84 MAOB (0.37) LIMK1MAOBRXRARXRBPDK2
SCHEMBL12865686 0.83 RXRA (0.48) RXRARXRBPDK2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 LIMK1 222/4885MAOB 446/4885RXRA 3214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.