Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686363 | 1.00 | MAPT (0.39) | MAPTL3MBTL1TSHRESR1ALDH1A1 | |
| SCHEMBL13508266 | 0.92 | PTGDR2 (0.42) | MAPTL3MBTL1PTGDR2 | |
| SCHEMBL3679163 | 0.92 | PTGDR2 (0.42) | MAPTL3MBTL1PTGDR2 | |
| SCHEMBL5175114 | 0.86 | ALDH1A1 (0.40) | MAPTL3MBTL1TSHRESR1ALDH1A1 | |
| SCHEMBL13508357 | 0.86 | ESR1 (0.39) | MAPTTSHRESR1ALDH1A1GAA | |
| SCHEMBL3690133 | 0.84 | PPARD (0.46) | L3MBTL1PTGDR2 | |
| SCHEMBL13508255 | 0.84 | PPARD (0.46) | L3MBTL1PTGDR2 | |
| SCHEMBL14339036 | 0.82 | PTGDR2 (0.42) | L3MBTL1PTGDR2 | |
| SCHEMBL3693445 | 0.82 | PTGDR2 (0.42) | L3MBTL1PTGDR2 | |
| SCHEMBL13508273 | 0.82 | PTGDR2 (0.42) | L3MBTL1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |