Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 9/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508799 | 0.87 | KCNH2 (0.59) | CYP11B1CYP11B2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL13508796 | 0.85 | QPCT (0.56) | HTTSMN1; SMN2BRD4NR1I2GHSR | |
| SCHEMBL13508797 | 0.84 | HTT (0.52) | CYP11B1CYP11B2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL13187230 | 0.81 | CYP11B1 (0.71) | CYP11B1CYP11B2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL9671643 | 0.80 | CYP11B1 (0.65) | CYP11B1CYP11B2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL9127426 | 0.79 | ALDH1A1 (0.57) | HTTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL13187037 | 0.76 | KCNH2 (0.71) | CYP11B1CYP11B2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL13187035 | 0.76 | CYP11B1 (0.63) | CYP11B1CYP11B2MAPK1HTTSMN1; SMN2 | |
| SCHEMBL17845423 | 0.76 | CA12 (0.44) | HTTNR1I2CA12CA1CA2 | |
| SCHEMBL1539109 | 0.76 | CA9 (0.44) | NR1I2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100028299-A1 | Methods and compositions of treating a flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-02-04 | — | — | US | disclosed |
| US-20100028299-A1 | Methods and compositions of treating a flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028299-A1 | Methods and compositions of treating a flaviviridae family viral infection | EIF2AK2, NSUN3, NSUN2 | CYP11B1 3424/4885CYP11B2 3502/4885MAPK1 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.