SCHEMBL135107

SCHEMBL135107

COc1cccc(C(C)N)c1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.56
AOC3 Q16853 3/20 0.53
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
CASR P41180 3/20 0.50
ACHE P22303 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617765 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL29676707 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL335349 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL335622 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL29350839 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
Hydrochloric Acid SCHEMBL16345210 0.98 TAAR1 (0.55) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
Hydrochloric Acid SCHEMBL12495550 0.98 TAAR1 (0.55) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL10781087 0.85 AOC3 (0.54) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL10781776 0.85 AOC3 (0.54) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL8204131 0.84 TAAR1 (0.53) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925626-B Novel aporphine compound and preparation method and application thereof 中国药科大学 2025-06-13 CN claimed
CN-118420612-A Target protein degradation compound based on CDK4/6 inhibitor and preparation method and application thereof 沈阳药科大学 2024-08-02 CN claimed
CN-115894365-B Synthesis method of tetrahydroisoquinoline compound and intermediate thereof 南方科技大学坪山生物医药研究院 2024-07-02 CN claimed
CN-117560937-A Perovskite solar cell based on 3-methoxy phenethylamine passivating agent and preparation method thereof 常州大学 2024-02-13 CN claimed
CN-114804989-B Purification method and racemization recycling of rivastigmine key chiral intermediate 华中科技大学 2023-12-26 CN claimed
CN-117082953-A Optoelectronic device and method for producing the same 天合光能股份有限公司 2023-11-17 CN claimed
EP-3688131-B1 COMPOSITIONS AND METHODS FOR PREVENTING COLLAPSE OF HIGH ASPECT RATIO STRUCTURES DURING DRYING VERSUM MAT US LLC (US) 2023-08-09 EP claimed
CN-115925626-A Novel aporphine compound and preparation method and application thereof 中国药科大学 2023-04-07 CN claimed
EP-4157233-A1 TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES Zydus Lifesciences Limited (IN) 2023-04-05 EP claimed
CN-115894365-A Synthesis method of tetrahydroisoquinoline compound and intermediate thereof 南方科技大学坪山生物医药研究院 2023-04-04 CN claimed
EP-1509497-A1 CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES Amgen Inc. (US) 2005-03-02 EP claimed
WO-2003099776-A1 CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES AMGEN INC. (US) 2003-12-04 WO claimed
EP-0848065-B1 Method for improving optical purity of an amine compound SUMITOMO CHEMICAL CO (JP) 2003-04-02 EP claimed
US-5965432-A PREFERENTIALLY METABOLIZING (S) ENANTOMORPH OF MIXTURE USING CULTURE OF ARTHROBACTER, CULTURE LIQUID, GEL IMMOBILIZED CELLS, FREEZE-DRIED OR ACETONE-DRIED CELLS, GROUND OR AUTODIGESTED CELLS, ULTRASONIC TREATED OR EXTRACTED CELLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-10-12 US claimed
EP-0848065-A2 Method for improving optical purity of an amine compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-06-17 EP claimed
US-5648540-A Amine preparation NPS PHARMACEUTICALS, INC. (US) 1997-07-15 US claimed
WO-1996002492-A1 METHOD OF MAKING A BENZYLPROPANAMINE NSP PHARMACEUTICALS, INC. (US) 1996-02-01 WO claimed
EP-0474200-B1 Process for the resolution of racemic 2,2-dimethyl cyclopropane carboxylic acid LONZA AG (CH) 1994-12-14 EP claimed
US-5166417-A PROCESS FOR RESOLUTION OF RACEMATES OF 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID LONZA LTD. (CH) 1992-11-24 US claimed
EP-0474200-A2 Process for the resolution of racemic 2,2-dimethyl cyclopropane carboxylic acid LONZA AG (CH) 1992-03-11 EP claimed