SCHEMBL335349

SCHEMBL335349

COc1cccc([C@H](C)N)c1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.56
AOC3 Q16853 3/20 0.53
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
CASR P41180 3/20 0.50
ACHE P22303 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617765 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL135107 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL29676707 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL335622 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL29350839 1.00 TAAR1 (0.56) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
Hydrochloric Acid SCHEMBL16345210 0.98 TAAR1 (0.55) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
Hydrochloric Acid SCHEMBL12495550 0.98 TAAR1 (0.55) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL10781087 0.85 AOC3 (0.54) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL10781776 0.85 AOC3 (0.54) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1
SCHEMBL8204131 0.84 TAAR1 (0.53) TAAR1AOC3ALDH1A1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2025-12-25 US claimed
EP-4565233-A1 TREATMENT FOR APLASTIC ANEMIA (AA) Zydus Lifesciences Limited (IN) 2025-06-11 EP claimed
EP-4539934-A1 TREATMENT FOR GLOMERULAR DISEASES Zydus Lifesciences Limited (IN) 2025-04-23 EP claimed
US-20250078176-A1 ENVIRONMENTAL ATTRIBUTES FOR NITROGEN CONTAINING CHEMICALS BASF SE (DE) 2025-03-06 US claimed
CN-119162143-A High-conversion rate transaminase mutant, encoding gene and application thereof 浙江大学 2024-12-20 CN claimed
CN-118435582-A Environmental attributes of nitrogen-containing chemicals 巴斯夫欧洲公司 2024-08-02 CN claimed
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA ZYDUS LIFESCIENCES LTD. (IN) 2024-05-30 US claimed
WO-2024028744-A1 TREATMENT FOR APLASTIC ANEMIA (AA) ZYDUS LIFESCIENCES LIMITED (IN) 2024-02-08 WO claimed
WO-2023248193-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2023-12-28 WO claimed
CN-114804989-B Purification method and racemization recycling of rivastigmine key chiral intermediate 华中科技大学 2023-12-26 CN claimed
WO-2010063774-A1 NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-06-10 WO claimed
WO-2009147687-A2 AN IMPROVED PROCESS FOR THE SEPARATION OF ENANTIOMERICALLY PURE COMPOUNDS SHODHANA LABORATORIES LIMITED (IN) 2009-12-10 WO claimed
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-11-12 US claimed
EP-2098519-A1 Process for the synthesis of ramelteon and its intermediates Teva Pharmaceutical Industries Ltd. (IL) 2009-09-09 EP claimed
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-03-12 US claimed
US-20080255383-A1 PREPARATION OF RIVASTIGMINE AND ITS SALTS DR. REDDY'S LABORATORIES, INC. 2008-10-16 US claimed
EP-1980552-A2 A process for the preparation of rivastigmine or a salt thereof Dr. Reddy's Laboratories Ltd. (IN) 2008-10-15 EP claimed
US-20060229315-A1 3-Substituted Quinoline-4-Carboxamide Derivatives as NK-3 and NK-2 Receptor Antagonists GLAXOSMITHKLINE S.P.A. (IT) 2006-10-12 US claimed
EP-1659120-A1 3-substituted quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists GlaxoSmithKline S.p.A. (IT) 2006-05-24 EP claimed
US-20040180902-A1 3-Substituted quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists SMITHKLINE BEECHAM S.P.A. (IT) 2004-09-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 TAAR1 2524/4885AOC3 3117/4885ALDH1A1 1460/4885
US-20040180902-A1 3-Substituted quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists HRH4, HRH2, HRH3 TAAR1 659/4885AOC3 1399/4885ALDH1A1 3625/4885
US-20080255383-A1 PREPARATION OF RIVASTIGMINE AND ITS SALTS ACHE, EHMT1, BCHE TAAR1 3130/4885AOC3 957/4885ALDH1A1 1784/4885
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES SSB, GRN, ALB TAAR1 4597/4885AOC3 1505/4885ALDH1A1 3041/4885
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 TAAR1 2307/4885AOC3 2448/4885ALDH1A1 1428/4885
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA HBG1, HBB, HBG2 TAAR1 4317/4885AOC3 2123/4885ALDH1A1 240/4885
US-20060229315-A1 3-Substituted Quinoline-4-Carboxamide Derivatives as NK-3 and NK-2 Receptor Antagonists KCNK3, KCNJ2, KCNK2 TAAR1 916/4885AOC3 2019/4885ALDH1A1 2590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.