Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2841193 | 0.99 | PHGDH (0.41) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL12193688 | 0.88 | CTSS (0.41) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL12193690 | 0.85 | CTSS (0.41) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL12193694 | 0.85 | CTSS (0.46) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL12193693 | 0.84 | CTSS (0.42) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL13512993 | 0.84 | CTSS (0.42) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL2845514 | 0.84 | CTSS (0.48) | CTSSCTSLTACR2 | |
| SCHEMBL2845533 | 0.84 | CTSS (0.48) | CTSSCTSLTACR2 | |
| SCHEMBL3626382 | 0.83 | CTSS (0.45) | PHGDHCTSSCTSLMEN1KMT2A | |
| SCHEMBL5258047 | 0.79 | CHRNA7 (0.54) | PHGDHMEN1KMT2ACHRNA7MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141147-A1 | ORNITHINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-01-06 | — | — | EP | disclosed |