Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 12/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22208259 | 1.00 | SQOR (0.84) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL29442277 | 1.00 | SQOR (0.84) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL22215650 | 0.92 | SQOR (1.00) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL22208218 | 0.88 | SQOR (0.77) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL29442355 | 0.88 | SQOR (0.77) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL22208347 | 0.88 | SQOR (0.86) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL29442436 | 0.88 | SQOR (0.86) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL22208233 | 0.86 | SQOR (1.00) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL22215864 | 0.86 | SQOR (1.00) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL22208252 | 0.86 | SQOR (0.84) | SQORKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007756-A1 | PYRIDINE DERIVATIVE HAVING TTK INHIBITION ACTIVITY | 塩野義製薬株式会社 (JP) | 2010-01-21 | — | — | WO | disclosed |