⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,3-Difluoro-Piperidinium SCHEMBL16415145 | 1.00 | — | — | |
| 3,3-Difluoro-Piperidinium SCHEMBL230371 | 0.97 | — | — | |
| 3,3-Difluoro-Piperidinium SCHEMBL27771281 | 0.97 | — | — | |
| SCHEMBL19320328 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL2572038 | 0.89 | ALDH1A1 (0.33) | — | |
| SCHEMBL16925525 | 0.89 | ALDH1A1 (0.40) | — | |
| 3,3-Difluoro-Piperidinium SCHEMBL20979780 | 0.84 | KDM4E (0.31) | — | |
| SCHEMBL91644 | 0.81 | — | — | |
| SCHEMBL22183528 | 0.81 | CXCR4 (0.41) | — | |
| Piperidine SCHEMBL28268097 | 0.81 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526209-B1 | HETEROCYCLIC APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF | RES TRIANGLE INST (US) | 2025-04-16 | — | — | EP | claimed |
| CN-119352167-A | Silver/bismuth double perovskite crystal and preparation method and application thereof | 金陵科技学院 | 2025-01-24 | — | — | CN | claimed |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | claimed |
| CN-117682981-A | Preparation method of gemagliptin prodrug | 中国科学院大连化学物理研究所 | 2024-03-12 | — | — | CN | claimed |
| CN-111233750-B | 3, 3-difluoro-1, 2,3, 6-tetrahydropiperidine derivative and preparation method thereof | 艾琪康医药科技（上海）有限公司 | 2023-12-05 | — | — | CN | claimed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | claimed |
| US-20220372018-A1 | KIF18A INHIBITORS | AMGEN INC. (US) | 2022-11-24 | — | — | US | claimed |
| EP-4048662-A1 | BICYCLO[1.1.1]PENTANE INHIBITORS OF DUAL LEUCINE ZIPPER (DLK) KINASE FOR THE TREATMENT OF DISEASE | Board of Regents, The University of Texas System (US) | 2022-08-31 | — | — | EP | claimed |
| EP-4007638-A1 | PYRIDINE DERIVATIVES AS KIF18A INHIBITORS | Amgen Inc. (US) | 2022-06-08 | — | — | EP | claimed |
| CN-111233750-A | 3, 3-difluoro-1, 2,3, 6-tetrahydropyridine derivatives and preparation method thereof | 艾琪康医药科技（上海）有限公司 | 2020-06-05 | — | — | CN | claimed |
| WO-2007137955-A1 | PIPERIDINYL PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-12-06 | — | — | WO | claimed |
| WO-2007100851-A1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070203154-A1 | Therapeutic Compounds | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2007-08-30 | — | — | US | claimed |
| WO-2007068620-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-21 | — | — | WO | claimed |
| US-20070142359-A1 | Pyrrolo [2,3-c] pyridine derivatives | HOFFMANN-LA ROCHE INC. | 2007-06-21 | — | — | US | claimed |
| WO-2007068641-A1 | PYRROLO [2 , 3-B] PYRIDINE DERIVATIVES AS H3 RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-21 | — | — | WO | claimed |
| US-20070142358-A1 | Pyrrolo [2,3-B] pyridine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-21 | — | — | US | claimed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | claimed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | claimed |
| WO-2003090680-A2 | NOVEL PHENYL DERIVATIVES AS INDUCERS OF APOPTOSIS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-06 | — | — | WO | claimed |