Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646988 | 1.00 | ADORA2A (0.41) | ADORA2APIK3CDRIPK1 | |
| SCHEMBL644948 | 0.90 | ADORA2A (0.41) | ADORA2APIK3CD | |
| SCHEMBL648257 | 0.88 | ADORA2A (0.40) | ADORA2A | |
| SCHEMBL14140992 | 0.88 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL13519782 | 0.86 | ADORA2A (0.44) | ADORA2APIK3CD | |
| SCHEMBL13531953 | 0.85 | ADORA2A (0.43) | ADORA2APIK3CD | |
| SCHEMBL7598953 | 0.85 | ADORA2A (0.43) | ADORA2APIK3CD | |
| SCHEMBL13531963 | 0.85 | ADORA2A (0.43) | ADORA2A | |
| SCHEMBL645160 | 0.85 | ADORA2A (0.43) | ADORA2A | |
| SCHEMBL646044 | 0.85 | ADORA2A (0.43) | ADORA2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002877-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-01-07 | — | — | WO | disclosed |