Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646988 | 0.88 | ADORA2A (0.41) | PIK3CD | |
| SCHEMBL13519772 | 0.88 | ADORA2A (0.41) | PIK3CD | |
| SCHEMBL14141080 | 0.83 | PIK3CD (0.44) | PIK3CD | |
| SCHEMBL14140993 | 0.80 | ACVRL1 (0.32) | PIK3CD | |
| SCHEMBL644948 | 0.77 | ADORA2A (0.41) | PIK3CD | |
| SCHEMBL648257 | 0.76 | ADORA2A (0.40) | — | |
| SCHEMBL13531968 | 0.73 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL13519782 | 0.72 | ADORA2A (0.44) | PIK3CD | |
| SCHEMBL7602181 | 0.72 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL13531953 | 0.72 | ADORA2A (0.43) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089105-A2 | ANTIVIRAL NUCLEOSIDE ANALOGS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-07-24 | — | — | WO | disclosed |