SCHEMBL135199

SCHEMBL135199

O=[PH](O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.45
BLM P54132 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
BTN3A1 O00481 3/20 0.34
MVD P53602 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17533843 1.00 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL28246888 0.97 FDPS (0.43) FDPSBLMTDP1BTN3A1
SCHEMBL9644784 0.95 FDPS (0.41) FDPSBLMTDP1BTN3A1
SCHEMBL10896986 0.83 FDPS (0.32) FDPSBLMTDP1
Phosphonic Acid SCHEMBL30714054 0.80 FDPS (0.30) FDPSBLMTDP1
SCHEMBL28642940 0.80 FDPS (0.30) FDPSBLMTDP1
Ammonia Solution, Strong SCHEMBL28600425 0.80 FDPS (0.30) FDPSBLMTDP1
Methane SCHEMBL10859496 0.80 FDPS (0.30) FDPSBLMTDP1
Triphosphate SCHEMBL9644789 0.80 FDPS (0.53) FDPSBLMTDP1BTN3A1MVD
SCHEMBL28161857 0.80 FDPS (0.30) FDPSBLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351840-B2 Reverse transcriptase mixtures with improved storage stability BIO-RAD LABORATORIES, INC. (US) 2019-07-16 US claimed
US-20190194640-A9 REVERSE TRANSCRIPTASE MIXTURES WITH IMPROVED STORAGE STABILITY BIO-RAD LABORATORIES, INC. 2019-06-27 US claimed
US-20160369260-A1 REVERSE TRANSCRIPTASE MIXTURES WITH IMPROVED STORAGE STABILITY BIO RAD LABORATORIES INC (US) 2016-12-22 US claimed
US-9458484-B2 Reverse transcriptase mixtures with improved storage stability BIO-RAD LABORATORIES, INC. (US) 2016-10-04 US claimed
US-20120129238-A1 REVERSE TRANSCRIPTASE MIXTURES WITH IMPROVED STORAGE STABILITY BIO-RAD LABORATORIES, INC. (US) 2012-05-24 US claimed
WO-2012054727-A1 REVERSE TRANSCRIPTASE MIXTURES WITH IMPROVED STORAGE STABILITY BIO-RAD LABORATORIES, INC. (US) 2012-04-26 WO claimed
US-20110003700-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION HUMAN GENETIC SIGNATURES PTY LTD. (AU) 2011-01-06 US claimed
US-6727059-B1 ADMINISTERING A NUCLEOSIDE ANALOG THAT HAS A 3' HYDROXYL GROUP LOCATED ON THE C3' CARBON OF THE 2'-DEOXYRIBOSE, FOR EXAMPLE DUTP; FOR RETROID VIRUS INFECTIONS SUCH AS HIV; MIXTURE WITH REVERSE TRANSCRIPTASE INHIBITORS SUCH AS AZT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-04-27 US claimed
EP-1200097-A2 METHOD FOR CONTROLLING THE FIDELITY AND THE EXECUTION OF REVERSE TRANSCRIPTASE BY INCORPORATING AND POLYMERISING NUCLEOTIDE ANALOGUES ACCEPTED AS SUBSTRATES OF THE REVERSE TRANSCRIPTION RESPONSE WITHOUT BLOCKING ITS ELONGATION Vigilent Technologies (FR) 2002-05-02 EP claimed
WO-2000067698-A2 METHOD FOR CONTROLLING THE FIDELITY AND EXECUTION OF REVERSE TRANSCRIPTASE BY INCORPORATING AND POLYMERISING NUCLEOTIDE ANALOGUES ACCEPTABLE AS SUBSTRATES WITHOUT BLOCKING ITS ELONGATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2000-11-16 WO claimed
WO-1998038297-A1 SINGLE STEP ASSEMBLY OF MULTIPLE DNA FRAGMENTS GESHER - ISRAEL ADVANCED BIOTECS (1996) LTD. (IL) 1998-09-03 WO claimed
EP-0360676-A1 Method for sequencing of nucleic acids COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-03-28 EP claimed
CN-117797276-A Application of sirt3 and sirt4 double-gene plasmids to gene therapy of mitochondrial encephalomyopathy 广州弘润生物科技有限公司 2024-04-02 CN disclosed
WO-2024015992-A1 SYSTEMS, METHODS, AND COMPOSITIONS FOR DIGITAL DROP-OFF ASSAYS ChromaCode, Inc. (US) 2024-01-18 WO disclosed
WO-2024011184-A1 METHODS AND SYSTEMS FOR DIGITAL MULTIPLEX ANALYSIS ChromaCode, Inc. (US) 2024-01-11 WO disclosed
US-20230357835-A1 MANIPULATING THE TRANSLATION OF DNA STRANDS ACROSS AND THROUGH NANOPORE SEQUENCING SYSTEMS USING RAMAN SIGNATURES TO IDENTIFY DNA BASES AND METHODS ARMONICA TECHNOLOGIES, INC. 2023-11-09 US disclosed
EP-0146589-A1 PROCESS FOR GENETIC MAPPING AND CROSS-BREEDING THEREON FOR PLANTS PLANT RESOURCES INSTITUTE (US) 1985-07-03 EP disclosed
EP-0133671-A2 Detection of bacteria by nucleic acid hybridization, labeled probes and test kit therefore MILES INC. (US) 1985-03-06 EP disclosed
EP-0133288-A2 Bacterial detection by nucleic acid hybridization, labeled probes and test kit therefore MILES LABORATORIES, INC. (US) 1985-02-20 EP disclosed
WO-1984004758-A1 PROCESS FOR GENETIC MAPPING AND CROSS-BREEDING THEREON FOR PLANTS PLANT RESOURCES INST (US) 1984-12-06 WO disclosed