Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521949 | 0.88 | CYP3A4 (0.49) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL348018 | 0.87 | CYP3A4 (0.68) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL1572613 | 0.87 | CYP3A4 (0.48) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL13521950 | 0.86 | CYP3A4 (0.49) | CYP3A4PTGDR2P2RX4CYP2C9SLC6A3 | |
| SCHEMBL349800 | 0.86 | CYP3A4 (0.54) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL347634 | 0.85 | CYP3A4 (0.47) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL348013 | 0.84 | CYP3A4 (0.52) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL12375393 | 0.84 | CYP3A4 (0.45) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL349244 | 0.83 | CYP3A4 (0.45) | CYP3A4PTGDR2PTGDRP2RX4CYP2C8 | |
| SCHEMBL13521962 | 0.83 | CYP3A4 (0.61) | CYP3A4PTGDR2PTGDRP2RX4NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003127-A2 | ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |