Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521894 | 0.89 | TSHR (0.41) | TSHRTHRBMAPK1MEN1KMT2A | |
| SCHEMBL685593 | 0.83 | TSHR (0.35) | TSHR | |
| SCHEMBL12649328 | 0.83 | TSHR (0.39) | TSHRTHRB | |
| SCHEMBL10136387 | 0.83 | TSHR (0.42) | TSHRTHRB | |
| SCHEMBL684929 | 0.82 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL13522017 | 0.81 | MEN1 (0.31) | THRBMAPK1MEN1KMT2A | |
| SCHEMBL685590 | 0.80 | TSHR (0.37) | TSHR | |
| SCHEMBL684912 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL684921 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL685525 | 0.79 | TSHR (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298746-B2 | Chemically amplified positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20100010129-A1 | CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-14 | — | — | US | disclosed |