Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523144 | 0.97 | NPC1 (0.44) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13523156 | 0.96 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13522973 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13523138 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13522964 | 0.92 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13523151 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13523146 | 0.87 | KDM4E (0.40) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13523154 | 0.86 | NPC1 (0.45) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13523142 | 0.84 | NPC1 (0.44) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13522977 | 0.84 | NPC1 (0.44) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |